| Gliomatosis cerebri mimicking chemotherapy-induced leukoencephalopathy in a patient with non-Hodgkin's lymphoma. | |
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MedLine Citation:
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PMID: 20371962 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Patients with hematological malignancies may develop white matter lesions, which are usually associated with chemotherapy. Magnetic resonance imaging (MRI) is the imaging modality of choice for identifying chemotherapy-induced, or "toxic", leukoencephalopathy. Brain biopsy in patients with hematological malignancies suspected of sustaining toxic leukoencephalopathy has rarely been performed, because its characteristic MRI findings are considered pathognomotic. Biopsy may be indicated in atypical cases, however, and it may yield unexpected results. We describe a case with white matter lesions that developed in an elderly man treated for non-Hodgkin's lymphoma. The lesions, initially diagnosed with toxic leukoencephalopathy based on MRI findings, turned out to be gliomatosis cerebri. |
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Authors:
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Joji Inamasu; Masashi Nakatsukasa; Takumi Kuramae; Yoshihiro Masuda; Kazuhiro Tomiyasu; Taketo Yamada |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-04-01 |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 49 ISSN: 1349-7235 ISO Abbreviation: Intern. Med. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-04-07 Completed Date: 2010-11-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: Japan |
Other Details:
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Languages: eng Pagination: 701-5 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, Saiseikai Utsunomiya Hospital, Utsunomiya. ginamasu@aol.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antineoplastic Combined Chemotherapy Protocols / adverse effects* Diagnosis, Differential Humans Leukoencephalopathies / chemically induced, diagnosis*, therapy Lymphoma, Non-Hodgkin / diagnosis*, therapy Male Neoplasms, Neuroepithelial / diagnosis*, therapy |
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