Document Detail


Glioma stem cells: not all created equal.
MedLine Citation:
PMID:  19345322     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A growing body of evidence suggests that only a small subpopulation of malignant glioma cells have true tumorigenic potential. A study by Peñuelas et al. in this issue of Cancer Cell demonstrates that TGF-beta can stimulate self-renewal and inhibit differentiation in a proportion of these glioma-initiating cells.
Authors:
Howard A Fine
Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Cancer cell     Volume:  15     ISSN:  1878-3686     ISO Abbreviation:  Cancer Cell     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-04-06     Completed Date:  2009-04-21     Revised Date:  2009-05-20    
Medline Journal Info:
Nlm Unique ID:  101130617     Medline TA:  Cancer Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  247-9     Citation Subset:  IM    
Affiliation:
Center for Cancer Research, Neuro-Oncology Branch, National Cancer Institute, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA. hfine@mail.nih.gov
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MeSH Terms
Descriptor/Qualifier:
Animals
Brain Neoplasms / metabolism,  pathology*
Cell Differentiation / physiology
Glioma / metabolism,  pathology*
Humans
Neoplastic Stem Cells / pathology*
Transforming Growth Factor beta / physiology
Chemical
Reg. No./Substance:
0/Transforming Growth Factor beta
Comments/Corrections
Comment On:
Cancer Cell. 2009 Apr 7;15(4):315-27   [PMID:  19345330 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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