| Glioma stem cells: not all created equal. | |
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MedLine Citation:
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PMID: 19345322 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A growing body of evidence suggests that only a small subpopulation of malignant glioma cells have true tumorigenic potential. A study by Peñuelas et al. in this issue of Cancer Cell demonstrates that TGF-beta can stimulate self-renewal and inhibit differentiation in a proportion of these glioma-initiating cells. |
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Authors:
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Howard A Fine |
Publication Detail:
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Type: Comment; Journal Article |
Journal Detail:
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Title: Cancer cell Volume: 15 ISSN: 1878-3686 ISO Abbreviation: Cancer Cell Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-04-06 Completed Date: 2009-04-21 Revised Date: 2009-05-20 |
Medline Journal Info:
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Nlm Unique ID: 101130617 Medline TA: Cancer Cell Country: United States |
Other Details:
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Languages: eng Pagination: 247-9 Citation Subset: IM |
Affiliation:
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Center for Cancer Research, Neuro-Oncology Branch, National Cancer Institute, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA. hfine@mail.nih.gov |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Brain Neoplasms / metabolism, pathology* Cell Differentiation / physiology Glioma / metabolism, pathology* Humans Neoplastic Stem Cells / pathology* Transforming Growth Factor beta / physiology |
| Chemical | |
Reg. No./Substance:
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0/Transforming Growth Factor beta |
| Comments/Corrections | |
Comment On:
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Cancer Cell. 2009 Apr 7;15(4):315-27
[PMID:
19345330
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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