Document Detail

Glioma of the acoustic nerve.
MedLine Citation:
PMID:  7396789     Owner:  NLM     Status:  MEDLINE    
We report a case of astrocytoma of the acoustic nerve. Most gliomas arise from the brainstem, and seldom originate in the acoustic or other "true" cranial and spinal nerves. Clinical features of this rare acoustic tumor differ from those of brainstem gliomas, but are indistinguishable from typical acoustic neurilemoma. We discuss the diagnosis and histogenesis of glioma arising in the eighth cranial nerve. Demonstration of glial fibrillary acid protein, an antigen specific for astrocytes, is a new method of verifying the diagnosis. Review of the literature indicates that a few cases of epithelial-like tumors of peripheral nerves may have been of neuroepithelial origin. The evidence, however, generally is not sufficient to exclude the possibility of metastatic neoplasms or other tumors such as malignant schwannoma and melanoma. Most of these putative gliomas contained gland-like tissue, and did not have the morphologic appearance of astrocytoma, as in approximately five reported examples, and in our case.
V Kasantikul; J O Palmer; M G Netsky; M E Glasscock; J W Hays
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of otolaryngology (Chicago, Ill. : 1960)     Volume:  106     ISSN:  0003-9977     ISO Abbreviation:  Arch Otolaryngol     Publication Date:  1980 Aug 
Date Detail:
Created Date:  1980-09-28     Completed Date:  1980-09-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376526     Medline TA:  Arch Otolaryngol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  456-9     Citation Subset:  AIM; IM    
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MeSH Terms
Astrocytoma / diagnosis,  pathology*
Cranial Nerve Neoplasms / diagnosis,  pathology*
Vestibulocochlear Nerve Diseases / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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