| Glioblastoma with granular cell astrocytoma features: a case report and literature review. | |
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MedLine Citation:
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PMID: 20860896 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We present the case of a 69-year old patient with a contrast enhancing, partially cystic lesion of the right temporal lobe, involving the ventricle and extending into the occipital lobe. The resected tumor showed histological features of a glioblastoma with granular cell astrocytoma features, lacking amplification of the EGFR gene region and IDH1R132H mutation. Literature review of 59 cases showed a 12-month overall survival of 11.7% for high-grade and 40% for low-grade granular cell astrocytomas. In 35% more than one cerebral lobe was affected. These extended mass effects may explain the worse prognosis despite the relatively bland histology of the granular cell component. |
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Authors:
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J Schittenhelm; T Psaras |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Clinical neuropathology Volume: 29 ISSN: 0722-5091 ISO Abbreviation: Clin. Neuropathol. Publication Date: 2010 Sep-Oct |
Date Detail:
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Created Date: 2010-09-23 Completed Date: 2010-10-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8214420 Medline TA: Clin Neuropathol Country: Germany |
Other Details:
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Languages: eng Pagination: 323-9 Citation Subset: IM |
Affiliation:
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Institute of Brain Research, University Hospital, Eberhard Karls University of Tuebingen, Germany. jens.schittenhelm@med.uni-tuebingen.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Astrocytoma / diagnosis, pathology* Brain Neoplasms / diagnosis, pathology* Female Glioblastoma / diagnosis, pathology* Humans Temporal Lobe / pathology |
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