| Glioblastoma mimicking herpes simplex encephalitis. | |
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MedLine Citation:
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PMID: 22053231 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We report a case of 70-year-old man with glioblastoma presenting as acute encephalitic illness. The patient exhibited sudden onset of cognitive impairment and headache for 2 days. Initial brain MRI showed left temporal lobe hyperintensity, and cerebrospinal fluid cytology revealed a mild pleocytosis. The patient had initially improved after medical treatment with a presumptive diagnosis of herpes simplex encephalitis (HSE). After 8 months, the patient complained of recurrent seizures. A follow-up brain MRI revealed marked increases in size and surrounding perilesional edema in the left temporal lesion on T2-weighted images and a new contrast-enhancing lesion on gadolinium-enhanced T1-weighted images. Stereotactic brain biopsy revealed a glioblastoma. The atypical encephalitic presentation of glioblastoma should be considered if definitive evidence for the diagnosis of HSE cannot be obtained. |
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Authors:
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Tai-Seung Nam; Kang-Ho Choi; Myeong-Kyu Kim; Ki-Hyun Cho |
Publication Detail:
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Type: Journal Article Date: 2011-08-31 |
Journal Detail:
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Title: Journal of Korean Neurosurgical Society Volume: 50 ISSN: 1598-7876 ISO Abbreviation: J Korean Neurosurg Soc Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-11-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101467054 Medline TA: J Korean Neurosurg Soc Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 119-22 Citation Subset: - |
Affiliation:
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Department of Neurology, Chonnam National University Hwasun Hospital, Hwasun, Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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