| Glial tumourettes (glial microtumours): their clinical and histopathological manifestations. | |
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MedLine Citation:
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PMID: 8869709 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study represents our experience with eight cases (males: 4; females: 4; 13-47 years old, average age 28.5 years) of a "glial tumourette" (minute glioma), which measured less than 15 mm in diameter on an MRI. Four tumours were located in the frontal lobe, one in the rostrum of the corpus callosum, two in the midbrain, and one in the thalamus. The symptoms and signs lasted from two days to 15 months prior to diagnosis, and they consisted of epileptic seizures in five patients and increased intracranial pressure due to hydrocephalus resulting from aqueductal stenosis in three. All patients had a CT scan and an MRI as a part of their initial neuroimaging evaluations. While the CT findings failed to show the lesion in four patients, MRI demonstrated it in all cases. Five tumours were either totally or subtotally removed while the remaining three were biopsied. Histological examinations revealed six tumours to be low-grade gliomas (fibrillary astrocytoma: 4; oligoastrocytoma: 2) and two to be high-grade gliomas (anaplastic astrocytoma: 1; anaplastic oligodendroglioma: 1). Regarding adjuvant therapy, three patients received radiation and/or chemotherapy. One of the patients with midbrain fibrillary astrocytoma died of the disease 38 months after the operation, however, no evidence of progression in the remaining seven has been observed in the follow-up period ranging from five to 65 months after the operation (average: 25.4 months). The histogenesis of benign and malignant gliomas and the importance of surgical exploration in the management of such patients with minute intracerebral tumours are also discussed. |
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Authors:
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S Nishio; T Morioka; I Takeshita; M Fukui |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta neurochirurgica Volume: 138 ISSN: 0001-6268 ISO Abbreviation: Acta Neurochir (Wien) Publication Date: 1996 |
Date Detail:
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Created Date: 1997-01-17 Completed Date: 1997-01-17 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0151000 Medline TA: Acta Neurochir (Wien) Country: AUSTRIA |
Other Details:
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Languages: eng Pagination: 818-23 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, Faculty of Medicine, Kyushu University, Fukuoka, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Brain Neoplasms / pathology*, surgery Female Glioma / pathology*, surgery Humans Image Processing, Computer-Assisted Male Middle Aged Prognosis |
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