Document Detail

Glaucoma screening in Western Cameroon.
MedLine Citation:
PMID:  19701764     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To quantify glaucoma-related parameters in a rural African region. MATERIAL AND METHOD: In a population-based investigation, 635 persons in six villages underwent slit-lamp examination including investigation of the optic nerve head with a 90D lens and Goldmann applanation tonometry. The mean age of the persons was 49.4 +/- 19 years, minimum 5, maximum 90, median 52 years. The inferior, superior, nasal and temporal margin width of the optic nerve head (ONH) were estimated as fractions of the total disk diameter, thus allowing the evaluation of the horizontal and vertical cup-disk ratio (CDR), the ratio of the elliptical cup area to the total disk area (area CDR), and violations of the ISNT rule (Inferior>or=Superior>or=Nasal>or=Temporal ONH rim). RESULTS: Area CDR significantly increased with age, on average from 0.1 in the youngest to 0.47 in the oldest person, corresponding to an increase of linear CDR from 0.32 to 0.68. The total fraction of eyes exceeding an area CDR of 0.5 (i.e. linear 0.7) was 13.4%. In addition, the intraocular pressure (IOP) increased on average from 14 mmHg in the youngest to 20 mmHg in the oldest persons, but nevertheless many high CDR values were found in eyes with normal to moderately elevated IOP. Violations of the ISNT rule were found in approximately 25% of the eyes. Application of a combination of glaucoma criteria as commonly used in literature resulted in a total prevalence of 18.7% of the screened persons, corresponding to a prevalence of 8.2% after age correction for the--on average--very young Cameroonian population. CONCLUSION: Compared to Europe, glaucoma prevalence appears to be nearly an order of magnitude higher in this rural African population.
Paul-Rolf Preussner; Allegra Grossmann; Faustin Ngounou; Gabriel Kouogan; James Tamon
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Publication Detail:
Type:  Journal Article     Date:  2009-08-23
Journal Detail:
Title:  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie     Volume:  247     ISSN:  1435-702X     ISO Abbreviation:  Graefes Arch. Clin. Exp. Ophthalmol.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-12     Completed Date:  2009-12-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8205248     Medline TA:  Graefes Arch Clin Exp Ophthalmol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1671-5     Citation Subset:  IM    
University Eye Hospital, Langenbeckstr. 1, 55101 Mainz, Germany.
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MeSH Terms
Age Distribution
Aged, 80 and over
Cameroon / epidemiology
Glaucoma, Open-Angle / diagnosis*,  epidemiology*
Intraocular Pressure
Middle Aged
Optic Disk / pathology
Rural Population / statistics & numerical data
Tonometry, Ocular
Visual Acuity
Visual Fields
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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