Document Detail


Glaucoma medication and aqueous humor dynamics.
MedLine Citation:
PMID:  15744139     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE OF REVIEW: This review evaluates current concepts regarding the effects of glaucoma medication on aqueous humor dynamics and the impact of this on intraocular pressure control and drug selection in clinical practice. RECENT FINDINGS: Calculations based on the Friedenwald and Goldmann equations have predicted that glaucoma medications that increase pressure-sensitive aqueous outflow will dampen intraocular pressure spikes and therefore may be advantageous over drugs that do not increase outflow facility. SUMMARY: Further experimental research is required to verify the influence of increased outflow facility on intraocular pressure fluctuation and the effect of this on glaucoma progression.
Authors:
Jonathan G Crowston; Robert N Weinreb
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in ophthalmology     Volume:  16     ISSN:  1040-8738     ISO Abbreviation:  Curr Opin Ophthalmol     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-03-03     Completed Date:  2005-05-26     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9011108     Medline TA:  Curr Opin Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  94-100     Citation Subset:  IM    
Affiliation:
Hamilton Glaucoma Center, University of California San Diego, La Jolla, California 92093-0946, USA. jcrowston@eyecenter.ucsd.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Antihypertensive Agents / therapeutic use*
Aqueous Humor / secretion*
Glaucoma / drug therapy*,  metabolism
Humans
Chemical
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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