Document Detail


Glandular neoplasia and borderline endocervical reporting rates before and after conversion to the SurePath(TM) liquid-based cytology (LBC) system.
MedLine Citation:
PMID:  22081523     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Reporting rates for glandular neoplasia in 464,754 cervical samples reported at six laboratories in 12-month periods before and after the implementation of Surepath™ LBC processing are compared. The introduction of LBC processing is seen to have resulted in a significant (P = 0.001) increase in the detection rate for endocervical glandular neoplasia (from 2.2 per 10,000 tests to 3.9 per 10,000) while maintaining high levels of reporting specificity. An observed fall in the number of samples reported as showing borderline glandular neoplasia falls short of statistical significance, and the reporting of possible endometrial and 'other' glandular abnormalities appears to be unaffected. The underlying reasons for the observed improvement in detection of endocervical glandular neoplasia are discussed. Diagn. Cytopathol. 2011. © 2010 Wiley Periodicals, Inc.
Authors:
C Burnley; N Dudding; M Parker; P Parsons; C J Whitaker; W Young
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Publication Detail:
Type:  Journal Article     Date:  2010-11-02
Journal Detail:
Title:  Diagnostic cytopathology     Volume:  39     ISSN:  1097-0339     ISO Abbreviation:  Diagn. Cytopathol.     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8506895     Medline TA:  Diagn Cytopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  869-74     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Wiley Periodicals, Inc.
Affiliation:
North East, Yorkshire and The Humber Quality Assurance Reference Centre, Wallsend, Newcastle Upon Tyne, Tyne and Wear, England.
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