| Giving birth to a new brain: hormone exposures of pregnancy influence human memory. | |
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MedLine Citation:
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PMID: 20304563 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Mammalian pregnancy produces alterations in maternal physiology that are necessary for maintaining gestation, fetal development and parturition. These changes also may prepare the maternal brain for the unique demands of motherhood. Parous rodents exhibit long-term changes in neurological structure and function and human work suggests that other landmark events in the reproductive cycle, such as menarche and menopause, influence cognition. However, the influence of pregnancy on the human brain remains to be elucidated. This study indicates that verbal recall memory (but not recognition or working memory) diminishes during human pregnancy and that these decrements persist after parturition. Further, prenatal glucocorticoids and estrogen are associated with these alterations. To meet the challenges of motherhood, the female brain may be remodeled, a process that appears to be initiated prenatally. However, it is not often that adaptation is achieved without an associated cost. For the human, in the case of the new maternal brain, diminished memory performance may reflect such a cost. |
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Authors:
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Laura M Glynn |
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1271323 - General-practitioner maternity units. 3373453 - Development of hamster circadian rhythms: role of the maternal suprachiasmatic nucleus. 12289533 - Judgment, 7 july 1987. |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural Date: 2010-03-21 |
Journal Detail:
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Title: Psychoneuroendocrinology Volume: 35 ISSN: 1873-3360 ISO Abbreviation: Psychoneuroendocrinology Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-16 Completed Date: 2010-12-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7612148 Medline TA: Psychoneuroendocrinology Country: England |
Other Details:
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Languages: eng Pagination: 1148-55 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Psychology, Chapman University, Orange, CA 92866, USA. lglynn@chapman.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Brain / drug effects*, physiology* Female Hormones / blood, metabolism, pharmacology* Humans Memory / drug effects*, physiology Mental Recall Neuronal Plasticity / drug effects, physiology Parturition / physiology* Pattern Recognition, Visual / physiology Postpartum Period / physiology, psychology Pregnancy |
| Grant Support | |
ID/Acronym/Agency:
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5M01RR 00827-29/RR/NCRR NIH HHS; R01 HD-40967/HD/NICHD NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Hormones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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