Document Detail


Gitelman's syndrome in pregnancy: case report and review of the literature.
MedLine Citation:
PMID:  20100726     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Gitelman's syndrome (GS), a rare renal disorder, results in hypokalaemia, hypomagnesaemia, hypocalciuria and a metabolic alkalosis. It is unclear if an alteration in management is necessary or beneficial during pregnancy. A 32-year-old woman with GS was managed in her second pregnancy. Antenatally, the patient required 39 (principally day case) admissions to the hospital for intravenous (IV) therapy and received a cumulative total of 47 l of IV 0.9% saline solution, 47 doses of 20 mmol magnesium chloride and 46 doses of 80 mmol potassium chloride. She delivered a 2940-g female infant in excellent condition by caesarean section. We would suggest that close attention to maternal weight gain during pregnancy is an easily available clinical tool to assess adequacy of fluid and electrolyte repletion in this condition.
Authors:
Fergus P McCarthy; Ciara N Magee; William D Plant; Louise C Kenny
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-01-25
Journal Detail:
Title:  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association     Volume:  25     ISSN:  1460-2385     ISO Abbreviation:  Nephrol. Dial. Transplant.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-29     Completed Date:  2010-08-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706402     Medline TA:  Nephrol Dial Transplant     Country:  England    
Other Details:
Languages:  eng     Pagination:  1338-40     Citation Subset:  IM    
Affiliation:
The ANU Research Centre, Department of Obstetrics and Gynaecology, University College Cork, Cork University Maternity Hospital, Wilton, Cork. Fergus.mccarthy@ucc.ie
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Gitelman Syndrome / complications*
Humans
Hypocalcemia / etiology*
Hypokalemia / diagnosis*
Infant
Magnesium Deficiency / diagnosis*
Pregnancy
Prognosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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