Document Detail


Ginseng as a Potential Novel Addition to the Antikeloid Weaponry.
MedLine Citation:
PMID:  22318923     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Keloid scars are large protruding claw-shaped lesions that develop beyond the confines of the wound and uniquely appears only in humans. For thousands of years ginseng has been used in the traditional medicine in oriental countries. It occupies a prominent position in the list of the best-selling medicinal herbs in the world. Panax ginseng often called Asian or Korean ginseng, is the most extensively used and the best grade of ginseng and the term of 'ginseng' generally refers to Panax ginseng. Previous studies have revealed that ginseng inhibits NF-kappa B, TGF-β, IL-6, ACE and MMP-2 and these factors play a pivotal role in keloid formation pathogenesis. Therefore it could be reasoned that ginseng could be effective for the treatment of the keloid scars. Clinical studies by topical applications of iPanax notoginseng (800 µg/ml) are warranted. Copyright © 2012 John Wiley & Sons, Ltd.
Authors:
Nader Pazyar; Mohammad Omidian; Noorodin Jamshydian
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-8
Journal Detail:
Title:  Phytotherapy research : PTR     Volume:  -     ISSN:  1099-1573     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8904486     Medline TA:  Phytother Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 John Wiley & Sons, Ltd.
Affiliation:
Department of Dermatology, Jundishapur University of Medical Sciences, Ahvaz, Iran.
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