Document Detail


Gibberellin biosynthesis and its regulation.
MedLine Citation:
PMID:  22533671     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The GAs (gibberellins) comprise a large group of diterpenoid carboxylic acids that are ubiquitous in higher plants, in which certain members function as endogenous growth regulators, promoting organ expansion and developmental changes. These compounds are also produced by some species of lower plants, fungi and bacteria, although, in contrast to higher plants, the function of GAs in these organisms has only recently been investigated and is still unclear. In higher plants, GAs are synthesized by the action of terpene cyclases, cytochrome P450 mono-oxygenases and 2-oxoglutarate-dependent dioxygenases localized, respectively, in plastids, the endomembrane system and the cytosol. The concentration of biologically active GAs at their sites of action is tightly regulated and is moderated by numerous developmental and environmental cues. Recent research has focused on regulatory mechanisms, acting primarily on expression of the genes that encode the dioxygenases involved in biosynthesis and deactivation. The present review discusses the current state of knowledge on GA metabolism with particular emphasis on regulation, including the complex mechanisms for the maintenance of GA homoeostasis.
Authors:
Peter Hedden; Stephen G Thomas
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The Biochemical journal     Volume:  444     ISSN:  1470-8728     ISO Abbreviation:  Biochem. J.     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-04-26     Completed Date:  2012-07-09     Revised Date:  2014-10-14    
Medline Journal Info:
Nlm Unique ID:  2984726R     Medline TA:  Biochem J     Country:  England    
Other Details:
Languages:  eng     Pagination:  11-25     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Environment
Gene Expression Regulation, Developmental
Gene Expression Regulation, Plant
Gibberellins / biosynthesis*,  genetics
Homeostasis
Plant Development
Plants / genetics,  metabolism*
Grant Support
ID/Acronym/Agency:
BBS/E/C/00004951//Biotechnology and Biological Sciences Research Council; //Biotechnology and Biological Sciences Research Council
Chemical
Reg. No./Substance:
0/Gibberellins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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