Document Detail

Giant splenic cyst with high serum concentration of CA 19-9. Failure of treatment with percutaneous transcatheter drainage and injection of tetracycline.
MedLine Citation:
PMID:  8734353     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Recently, several cases of nonparasitic true splenic cyst with high serum concentration of carbohydrate antigen (CA 19-9) have been reported. CASE: We report a giant splenic cyst presenting with high serum concentration of CA 19-9 in a 21-year-old man without a history of previous trauma. Imaging techniques showed a huge monolocular cyst of the spleen, and laboratory data showed increased serum CA 19-9 levels (326 U/ml; normal, < 37 U/ml). Serologic test was negative for parasitic infection. These findings led us to the diagnosis of epithelial splenic cyst. Percutaneous transcatheter drainage and injection of tetracycline were performed for 2 weeks. The cyst shrank, and the serum CA 19-9 level decreased favorably. However, cystic fluid reaccumulated in a month. CONCLUSIONS: The accumulation of cystic fluid in splenic epithelial cysts may be attributable not only to the secretion of the lining cells but also to influx from the splenic sinuses.
H Yoshikane; T Suzuki; N Yoshioka; Y Ogawa; Y Hayashi; E Hamajima; T Yokoi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Scandinavian journal of gastroenterology     Volume:  31     ISSN:  0036-5521     ISO Abbreviation:  Scand. J. Gastroenterol.     Publication Date:  1996 May 
Date Detail:
Created Date:  1996-10-09     Completed Date:  1996-10-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0060105     Medline TA:  Scand J Gastroenterol     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  524-6     Citation Subset:  IM    
Dept. of Internal Medicine, Kariya General Hospital, Japan.
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MeSH Terms
CA-19-9 Antigen / blood*
Combined Modality Therapy
Cysts / blood,  diagnosis,  therapy*
Drainage / methods
Sclerosing Solutions / therapeutic use
Splenic Diseases / blood,  diagnosis,  therapy*
Tetracycline / therapeutic use
Treatment Failure
Reg. No./Substance:
0/CA-19-9 Antigen; 0/Sclerosing Solutions; 60-54-8/Tetracycline

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