Document Detail

Giant plexiform neurofibroma in a patient with neurofibromatosis type I.
MedLine Citation:
PMID:  19624985     Owner:  NLM     Status:  MEDLINE    
Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder primarily affecting the development and growth of nerve cell tissues. Plexiform neurofibroma is considered an uncommon skin tumor. The involvement of the genitourinary tract or the lower limb is rare, with bladder, upper urinary tract and genital involvement reported in decreasing order of frequency. The management of patients with plexiform neurofibroma is not well defined and aiming mostly at controlling symptoms. We present a case of a giant genitourinary plexiform neurofibroma associated with lower limb gigantism in a patient with NF1.
Efstathios Rallis; Dimitra Ragiadakou
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-05-15
Journal Detail:
Title:  Dermatology online journal     Volume:  15     ISSN:  1087-2108     ISO Abbreviation:  Dermatol. Online J.     Publication Date:  2009  
Date Detail:
Created Date:  2009-07-23     Completed Date:  2009-10-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610776     Medline TA:  Dermatol Online J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  7     Citation Subset:  IM    
Department of Dermatology, Army General Hospital, Athens, Greece.
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MeSH Terms
Buttocks / pathology*
Diseases in Twins
Leg / pathology*
Neoplasm Invasiveness
Neurofibroma, Plexiform / genetics,  pathology*
Neurofibromatosis 1 / genetics,  pathology*
Scrotum / pathology
Soft Tissue Neoplasms / genetics,  pathology*
Urogenital Neoplasms / genetics,  pathology*
Young Adult

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