Document Detail

Giant lymph node hyperplasia a diagnostic dilemma in the neck.
MedLine Citation:
PMID:  11240329     Owner:  NLM     Status:  MEDLINE    
Giant lymph node hyperplasia (GLNH) or Castleman's disease is a rare pathological entity commonly presenting as a solitary mediastinal tumour (unifocal variant), although other anatomical sites have been reported including the head and neck, abdomen and axilla. Though the head and neck is the second commonest site for this lesion, only 60 cases [1,2] have been reported in the literature. Pre-operative diagnosis of the unifocal variant can be difficult as routine investigations carried out in the clinic setting are often inconclusive. A multicentric form of this disease with a poorer prognosis in comparison to the unifocal lesion has been described by Gaba et al. in 1978 [3]. We present a case of an unusually large, slow growing, asymptomatic, unifocal variant of this tumour restricted to the neck which underwent successful surgical excision. A review of the literature, histopathological characteristics and differential diagnosis is also presented.
V Raut; J Cullen; D Hughes
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Auris, nasus, larynx     Volume:  28     ISSN:  0385-8146     ISO Abbreviation:  Auris Nasus Larynx     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-03-12     Completed Date:  2001-05-31     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7708170     Medline TA:  Auris Nasus Larynx     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  185-8     Citation Subset:  IM    
Department of ENT, Altnagelvin Area Hospital, Glenshane Road, BT47 6SB, Londonderry, UK.
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MeSH Terms
Diagnosis, Differential
Giant Lymph Node Hyperplasia / diagnosis*,  pathology,  surgery
Tomography, X-Ray Computed

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