Document Detail

Giant liver hemangioma: the role of female sex hormones and treatment.
MedLine Citation:
PMID:  21399504     Owner:  NLM     Status:  Publisher    
Hepatic hemangiomas are the most common focal liver lesions and are especially prevalent in women. Giant hemangiomas are defined as hemangiomas of at least 4 cm in diameter and the majority remains stable in size over time. However, in some cases hemangiomas display growth and give rise to symptoms because of their space-occupying effect. Causes for the enlargement of the tumors are unknown, but a role of female sex hormones has been suggested. Therefore, hormone therapy should be avoided in patients who became symptomatic. In patients with important symptoms, disease control can be obtained by transcatheter arterial embolization. In selected patients, especially in case of Kasabach-Merritt syndrome, there is a good indication for liver transplantation.
Hannah van Malenstein; Geert Maleux; Diethard Monbaliu; Chris Verslype; Mina Komuta; Tania Roskams; Wim Laleman; David Cassiman; Johan Fevery; Raymond Aerts; Jacques Pirenne; Frederik Nevens
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-10
Journal Detail:
Title:  European journal of gastroenterology & hepatology     Volume:  -     ISSN:  1473-5687     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9000874     Medline TA:  Eur J Gastroenterol Hepatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
aDepartments of Hepatology bRadiology cAbdominal Transplant Surgery dPathology, University Hospital Gasthuisberg, KU Leuven, Belgium.
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