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Giant lipoma of the thenar--case study and contemporary approach to its aetiopathogenicity.
MedLine Citation:
PMID:  19093156     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Giant lipomas of the thenar are rare tumours of the adipose tissue of the hand, with a benign prognosis. Apart from the cosmetic problems they may cause, their most frequent complications include a compromise in functionality and pressure upon the nerves, mainly on the radial nerve. The first step in their management is their differential diagnosis from well-differentiated liposarcomas (WDLPS), as they require a different therapeutic approach. This step is completed with the aid of MRIs, biopsies and modern immunohistochemical methods, which offer high specificity and sensitivity. Our paper presents a case of giant lipoma of the thenar, with a review of the relevant literature, focusing on the disease's molecular genetics, which is a very important field of research today.
Authors:
T B Grivas; S A Psarakis; Alpha Kaspiris; G Liapi
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Publication Detail:
Type:  Journal Article     Date:  2008-12-18
Journal Detail:
Title:  Hand (New York, N.Y.)     Volume:  4     ISSN:  1558-9447     ISO Abbreviation:  Hand (N Y)     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-05-25     Completed Date:  2010-06-28     Revised Date:  2010-09-23    
Medline Journal Info:
Nlm Unique ID:  101264149     Medline TA:  Hand (N Y)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  173-6     Citation Subset:  -    
Affiliation:
Department of Trauma and Orthopaedics, Thriasio General Hospital-NHS, G. Gennimata Avenue, Magoula 19600 Attica, Greece. grivastb@vodafone.net.gr
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