Document Detail


Giant chalazia in the hyperimmunoglobulinemia E (hyper-IgE) syndrome.
MedLine Citation:
PMID:  15206652     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To report the occurrence of recurrent multiple giant chalazia in the hyperimmunoglobulin E syndrome (hyper-IgE syndrome or Job syndrome). METHODS: Two patients with hyperimmunoglobulinemia E (>500 IU/ml) had ophthalmologic examination and surgical treatment for chalazia of the eyelids. RESULTS: The hyper-IgE syndrome is a rare immunodeficiency and multisystem disorder characterized by recurrent skin and pulmonary abscesses, connective tissue abnormalities, and elevated levels of serum IgE. In two patients with the hyper-IgE syndrome, multiple giant chalazia were seen in upper and lower eyelids. Despite surgical incision new giant chalazia arose. CONCLUSIONS: Recurrent multiple giant chalazia may occur as an ophthalmic feature of the hyper-IgE syndrome.
Authors:
N Crama; A M P Toolens; J W M van der Meer; J R M Cruysberg
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of ophthalmology     Volume:  14     ISSN:  1120-6721     ISO Abbreviation:  Eur J Ophthalmol     Publication Date:    2004 May-Jun
Date Detail:
Created Date:  2004-06-21     Completed Date:  2004-07-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9110772     Medline TA:  Eur J Ophthalmol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  258-60     Citation Subset:  IM    
Affiliation:
Institute of Ophthalmology, University Medical Centre Nijmegen, Nijmegen, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Chalazion / complications*,  diagnosis,  surgery
Eyelids / pathology
Female
Humans
Job's Syndrome / complications*,  diagnosis
Male
Recurrence

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