Document Detail

Giant-cell temporal arteritis in a 17-year-old male.
MedLine Citation:
PMID:  16678704     Owner:  NLM     Status:  MEDLINE    
Temporal arteritis, particularly in its classic form, is exceedingly rare in individuals <50 years old. We report the youngest case of biopsy-proven giant cell temporal arteritis. A 17-year-old male presented with a progressively expanding and pulsatile but otherwise asymptomatic mass in his forehead. The patient's medical history was significant for uveitis since the age of 3, and severe allergic rhinitis, mild asthma, and juvenile rheumatoid arthritis as a young adolescent. Admission laboratory values included a mildly elevated erythrocyte sedimentation rate and C-reactive protein level. A computed tomography evaluation demonstrated aneurysmal degeneration of the frontal branch of the right superficial temporal artery and confirmed no other cerebrovascular changes. Histologically, the aneurysmal arterial segment demonstrated subacute temporal arteritis. The arterial wall had a primarily lymphoplasmacytic infiltrate with rare giant cells and focally marked medial destruction. Additionally, severely obstructive intimal hyperplasia with chronic adventitial and periadvential dense fibrosis was noted. The diagnosis of classic giant cell temporal arteritis was established from the biopsy result. Postoperatively, the patient was treated with prednisone for 3 months. Three years after surgery, the patient remains well and reports no recurrence of temporal artery disease.
Iraklis I Pipinos; Russell Hopp; William D Edwards; Stanley J Radio
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of vascular surgery     Volume:  43     ISSN:  0741-5214     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-05-08     Completed Date:  2006-05-30     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1053-5     Citation Subset:  IM    
Department of Surgery, University of Nebraska Medical Center, Omaha, USA.
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MeSH Terms
Aneurysm / diagnosis,  pathology,  surgery*
Diagnosis, Differential
Fibromuscular Dysplasia / diagnosis,  pathology
Giant Cell Arteritis / diagnosis,  pathology,  surgery*
Temporal Arteries / pathology,  surgery
Tomography, X-Ray Computed
Tunica Intima / pathology
Tunica Media / pathology
Comment In:
J Vasc Surg. 2006 Nov;44(5):1133-4   [PMID:  17098557 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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