| Giant cell and lymphocytic interstitial pneumonia associated with fetal pneumonia. | |
| | |
MedLine Citation:
|
PMID: 7855015 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In a review of 96 consecutive perinatal autopsies (42 nonautolyzed stillborn and 54 liveborn infants 12 h or less of age) with histologic sections of placental tissues and an undistended lung, we were impressed by the frequent occurrence of lymphocytic infiltrates in the interstitium of the lung. To study this phenomenon further we analyzed the cases for 56 clinicopathologic variables. Lymphocytic interstitial infiltrates were present in 22 of the cases, 5 stillborn and 17 liveborn. The severity of the infiltrates was highly significantly correlated with the severity of chorioamnionitis, funisitis, and fetal pneumonia (P < .001). A positive association was found with livebirth and a negative association with hyaline membrane disease (both P < .05). No significant association was found with gestational age, body size, or other complications of pregnancy, labor, delivery, or the immediate perinatal period. Twenty-seven cases had fetal pneumonia without lymphocytic interstitial infiltrates. Two cases had interstitial lymphocytic infiltrates in the absence of fetal pneumonia, but both had chorioamnionitis. Two other cases had numerous giant cells, shown to be of macrophage origin by immunoperoxidase stains, in the airways in addition to severe fetal pneumonia and lymphocytic interstitial pneumonia. The observations show that lymphocytic interstitial infiltrates and giant cells may be a feature of fetal pneumonia. |
| | |
Authors:
|
A R Sgrignoli; D R Yen; G M Hutchins |
Related Documents
:
|
17763455 - Ectopic pregnancy in a cesarean section scar treated with intramuscular methotrexate an... 11107525 - Methotrexate and the photodermatitis reactivation reaction: a case report and review of... 11056225 - Predictors of treatment failure for ectopic pregnancy treated with single-dose methotre... 19327765 - Laparoscopic management of a primary omental pregnancy after clomiphene induction. 994065 - Dynamics of contraceptive failures. 8607335 - Second trimester routine ultrasound and abnormal findings. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Pediatric pathology / affiliated with the International Paediatric Pathology Association Volume: 14 ISSN: 0277-0938 ISO Abbreviation: Pediatr Pathol Publication Date: 1994 Nov-Dec |
Date Detail:
|
Created Date: 1995-03-16 Completed Date: 1995-03-16 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8303527 Medline TA: Pediatr Pathol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 955-65 Citation Subset: IM |
Affiliation:
|
Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Female Fetal Diseases / pathology* Gestational Age Giant Cells / pathology* Humans Immunoenzyme Techniques Infant, Newborn Lung / pathology* Lung Diseases, Interstitial / pathology* Lymphocytes / pathology* Male Pneumonia / pathology* Retrospective Studies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Surfactant replacement therapy in preterm neonates: a comparison of postmortem pulmonary histology i...
Next Document: 46,XX gonadal agenesis in a neonate with multiple congenital anomalies: case report and review of th...