| Giant cell arteritis with CD8+ instead of CD4+ T lymphocytes as the predominant infiltrating cells in a young woman. | |
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MedLine Citation:
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PMID: 15340654 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Giant cell arteritis is rarely reported in people aged less than 50 years. We report a case of giant cell arteritis in a woman who developed symptoms of dizziness, headache, bilateral sensorineural hearing impairment, and had 1 episode of transient left hemiparesis before the age of 30. Carotid angiography showed multiple segmental narrowing in cranial vessels. Subsequently, at the age of 31, she had weight loss and developed a fever. Chest radiograph revealed mediastinal widening, and chest computed tomography revealed dilated pulmonary arteries and veins. Coronary angiography and aortography showed irregular narrowing of the descending aorta and multiple stenosis, with aneurysmal dilatation involving the proximal and distal coronary, pulmonary and mesenteric arteries. Multinucleated giant cells and predominant CD8+ T lymphocyte infiltration were noted in a left temporal artery biopsy specimen. The patient's age and the finding of dilated pulmonary veins and prominent CD8+ T lymphocytes in the biopsy specimen suggest that this case was a distinct form of systemic giant cell arteritis. |
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Authors:
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Chien-Sheng Wu; Kwan-Lih Hsu; Yih-Leong Chang; Kuang-Lun Lee |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi Volume: 37 ISSN: 1684-1182 ISO Abbreviation: J Microbiol Immunol Infect Publication Date: 2004 Aug |
Date Detail:
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Created Date: 2004-09-01 Completed Date: 2004-11-04 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100956211 Medline TA: J Microbiol Immunol Infect Country: China (Republic: 1949- ) |
Other Details:
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Languages: eng Pagination: 246-9 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Far East Memorial Hospital, Taipei, Taiwan, ROC. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult CD4-Positive T-Lymphocytes / immunology, pathology CD8-Positive T-Lymphocytes / immunology*, pathology Carotid Arteries / radiography Female Giant Cell Arteritis / diagnosis, immunology*, pathology Headache / etiology Hearing Loss / etiology Humans Stroke / etiology Temporal Arteries / pathology Tinnitus / etiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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