| Giant cell arteritis (temporal arteritis, cranial arteritis) and a case from Singapore. | |
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MedLine Citation:
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PMID: 14560864 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Giant cell arteritis as the underlying cause of blindness in the elderly is common in the West but is not seen except on rare occasions in South East Asia. We describe an 86-year-old Chinese man from Singapore who presented with a central retinal artery occlusion. Biopsy of a prominent superficial temporal artery established the underlying cause to be giant cell arteritis which was also the eventual cause of death as the condition resulted in rupture of a dissecting aneurysm of the aorta. Giant cell arteritis should be considered in all cases of ischaemic eye disease in the elderly. The importance of early diagnosis lies in the very high incidence of second eye involvement within days or at most weeks in untreated patients. A high index of suspicion is required for diagnosis of this condition which is likely under-diagnosed in our local context. |
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Authors:
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J F Cullen; C M L Chan; K L Chuah |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Singapore medical journal Volume: 44 ISSN: 0037-5675 ISO Abbreviation: Singapore Med J Publication Date: 2003 Jun |
Date Detail:
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Created Date: 2003-10-16 Completed Date: 2003-11-19 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0404516 Medline TA: Singapore Med J Country: Singapore |
Other Details:
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Languages: eng Pagination: 306-8 Citation Subset: IM |
Affiliation:
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Neuro-Ophthalmology Service, Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore 168751. jbarrycullen@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Aneurysm, Dissecting / etiology Anti-Inflammatory Agents / administration & dosage, therapeutic use Aortic Aneurysm / etiology Blindness / drug therapy, etiology* Fatal Outcome Giant Cell Arteritis / complications, diagnosis*, drug therapy Humans Male Prednisolone / administration & dosage, therapeutic use Retinal Artery Occlusion / complications, diagnosis*, drug therapy Singapore |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 50-24-8/Prednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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