| Giant cell arteritis incidence: analysis by season and year in mid-Atlantic United States. | |
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MedLine Citation:
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PMID: 23332080 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Evaluate the incidence of biopsy-proven giant cell arteritis (GCA) for seasonal or annual variability from a tertiary care center in the Mid-Atlantic United States. DESIGN: Retrospective chart review of all patients seen in the Neuro-Ophthalmology Service undergoing temporal artery biopsy (TAB) from 1994 to 2011. PARTICIPANTS: The charts of 744 patients were reviewed and 215 patients were diagnosed with GCA based on positive TAB results. METHODS: All results between 1994 and 2011 were reviewed. GCA incidence data was evaluated by year, season, and month for any trends or cyclic patterns. A subset of clinical charts was reviewed to determine time from symptoms to diagnosis. MAIN OUTCOME MEASURE: Incidence of biopsy proven GCA. RESULTS: The majority of patients were female (74%) and over the age of 60 (98.6 %). The diagnosis of biopsy-proven GCA was found in 215 of 744 (28.9%) patients. The incidence of biopsy proven GCA by year varied, with the peak incidence in 1996. The monthly incidence peaked in July and had a trough in October. However, Poisson regression analysis did not show any statistically significant trend over time or cyclic pattern to the incidence by year, season, or month. CONCLUSION: The incidence of biopsy-proven GCA in the population studied did not have any significant cyclic pattern over the last 17 years. The highest incidence by month was noted in July with a trough in October. However, this was not a significant pattern by month or season to support infectious or periodic environmental factors inciting GCA. |
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Authors:
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Krystian Kisza; Ann P Murchison; Yang Dai; Jurij R Bilyk; Ralph C Eagle; Robert Sergott; Peter J Savino |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-21 |
Journal Detail:
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Title: Clinical & experimental ophthalmology Volume: - ISSN: 1442-9071 ISO Abbreviation: Clin. Experiment. Ophthalmol. Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100896531 Medline TA: Clin Experiment Ophthalmol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2013 The Authors. Clinical and Experimental Ophthalmology © 2013 Royal Australian and New Zealand College of Ophthalmologists. |
Affiliation:
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Department of Ophthalmology, Wroclaw Medical University, Wroclaw, Poland. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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