| Giant cell arteritis: diagnosis, management, and cardiovascular implications. | |
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MedLine Citation:
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PMID: 17303991 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Giant cell arteritis is a relatively common form of systemic vasculitis, best known for its predisposition to affect the extracranial branches of the carotid artery and associated potential for visual loss. Additional vascular manifestations include stroke, aortic aneurysm or dissection, and even aortic rupture. Cardiac manifestations include coronary artery disease, aortic valve insufficiency, or left ventricular dysfunction, which may occur independently from the valvular disease or hypertension. Physicians need to be vigilant for this disorder, particularly because the tragic end-organ outcomes such as visual loss can be effectively prevented with early use of corticosteroids. We review the pathophysiology and clinical manifestations of giant cell arteritis and present a rationale for diagnosis and therapy for this disease. |
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Authors:
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Robert T Eberhardt; Mandeep Dhadly |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Cardiology in review Volume: 15 ISSN: 1538-4683 ISO Abbreviation: Cardiol Rev Publication Date: 2007 Mar-Apr |
Date Detail:
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Created Date: 2007-02-16 Completed Date: 2007-03-13 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9304686 Medline TA: Cardiol Rev Country: United States |
Other Details:
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Languages: eng Pagination: 55-61 Citation Subset: IM |
Affiliation:
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Vascular Medicine Program, Division of Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA. robert.eberhardt@bmc.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Cortex Hormones
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therapeutic use Adult Age Distribution Aged Diagnosis, Differential Europe / epidemiology Female Giant Cell Arteritis / diagnosis*, epidemiology, physiopathology, therapy* Humans Immunosuppressive Agents / therapeutic use Incidence Male Middle Aged Prognosis Sex Distribution Takayasu Arteritis / diagnosis, epidemiology Temporal Arteries / pathology, radionuclide imaging, ultrasonography |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Immunosuppressive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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