| Giant cell arteritis: diagnosing and treating inflammatory disease in older adults. | |
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MedLine Citation:
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PMID: 16092890 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Giant cell arteritis (GCA), also known as temporal arteritis, cranial arteritis, or granulomatous arteritis, is a systemic necrotizing vasculitis seen in patients typically over age 50. If untreated, GCA can cause permanent visual loss in one or both eyes in 13% to 50% of patients. Primary care physicians routinely see elderly patients with headaches and fatigue; these may be potential symptoms of GCA. C-reactive protein (CRP) in conjunction with erythrocyte sedimentation rate (ESR) has 97% specificity in diagnosing GCA. Temporal artery biopsy confirms the diagnosis in many cases. Early recognition and treatment of this potentially blinding condition is thus essential. Systemic steroids are the standard therapy for patients with a positive diagnosis of GCA, and in a high percentage of patients the treatment may extend for more than one year. |
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Authors:
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Syed S Azhar; Rosa A Tang; E Ulysses Dorotheo |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Geriatrics Volume: 60 ISSN: 0016-867X ISO Abbreviation: Geriatrics Publication Date: 2005 Aug |
Date Detail:
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Created Date: 2005-08-11 Completed Date: 2005-08-30 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985102R Medline TA: Geriatrics Country: United States |
Other Details:
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Languages: eng Pagination: 26-30 Citation Subset: AIM; IM |
Affiliation:
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Department of Family Medicine, University of Texas Medical Branch, Galveston, TX, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Giant Cell Arteritis / classification, diagnosis*, drug therapy* Glucocorticoids / therapeutic use Humans Middle Aged Optic Neuropathy, Ischemic / diagnosis Physical Examination Prednisolone / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Glucocorticoids; 50-24-8/Prednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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