| Ghrelin levels in cord blood from concordant and discordant twin pairs: association with birth weight and postnatal catch-up growth. | |
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MedLine Citation:
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PMID: 21121713 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Objective. To determine whether cord blood ghrelin levels in discordant and concordant twins predict postnatal catch-up growth. Methods. After obtaining parental consent, cord blood samples were collected at delivery for total ghrelin analysis. Infant weight, length and head circumference were obtained at birth, 2, 4, and 6 months of age. Data points post-discharge were obtained from the pediatrician's office or via parent contact. Pearson correlation evaluated the relationship between cord blood ghrelin levels and postnatal catch-up growth. Results. There was a statistically significant correlation between cord blood ghrelin levels and birth weight among concordant twins, but not among the discordant twins. Cord blood ghrelin levels did not predict postnatal growth at 6 months of age overall, but did so in the subset of monochorionic, discordant pairs. Conclusion. Cord blood ghrelin levels did not correlate overall with birth size or postnatal catch-up growth in concordant and discordant twin pairs, but did so in selected subsets. Further studies are needed. |
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Authors:
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Umair Sharih; Bhagya L Puppala; Ramona Donovan; Barbara V Parilla |
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Publication Detail:
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Type: Journal Article Date: 2010-12-01 |
Journal Detail:
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Title: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Volume: 24 ISSN: 1476-4954 ISO Abbreviation: J. Matern. Fetal. Neonatal. Med. Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-06-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101136916 Medline TA: J Matern Fetal Neonatal Med Country: England |
Other Details:
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Languages: eng Pagination: 875-9 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Division of Neonatology, Advocate Lutheran General Children's Hospital, Park Ridge, IL, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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