Document Detail

Gestational trophoblastic disease in ectopic pregnancy: A case series.
MedLine Citation:
PMID:  17086802     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To describe 6 cases of gestational trophoblastic disease (GTD) in ectopic pregnancy admitted to Hospital Universitario de Caracas (HUC). STUDY DESIGN: Medical records of 6 patients admitted to the Obstetrics and Gynecology Department, HUC, from 1996 to 2004 were reviewed. They underwent surgery with a diagnosis of ectopic pregnancy, and histologic analysis revealed GTD. Clinical trends were analyzed. RESULTS: The prevalence of GTD in ectopic pregnancy was 0.16:1,000 deliveries. The mean patient age was 29 years. The preceding gestation was a term delivery in 4 and abortion in 2. The mean gestational age at admission was 8 weeks. All patients complained of abdominal pain, and 3 of them also had vaginal bleeding. Ultrasound revealed an adnexal tumor in 5 cases; this tumor and hemoperitoneum (6 cases) were the most frequent surgical findings. Histopathologic diagnosis was partial mole in 5 and choriocarcinoma in 1. Four patients were lost to follow-up. CONCLUSION: In this series the prevalence of ectopic GTD was high. The condition can mimic the usual symptoms of ectopic pregnancy, especially when a hemoperitoneum is present. It is important to apply strict histologic criteria for GTD when a sample of ectopic pregnancy is analyzed and to monitor those patients with careful human chorionic gonadotropin follow-up.
Rafael Cortés-Charry; Lina M Figueira; Victoria García-Barriola; Carolina Gomez; Isabel Garcia; Carla Santiago
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  51     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-11-07     Completed Date:  2007-01-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  760-3     Citation Subset:  IM    
Obstetrics and Gynecology Department, Hospital Universitario de Caracas, Universidad Central de Venezuela, Venezuela.
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MeSH Terms
Gestational Trophoblastic Neoplasms / diagnosis,  epidemiology*,  etiology,  pathology
Medical Records
Pregnancy Outcome
Prenatal Diagnosis
Retrospective Studies
Uterine Neoplasms / diagnosis,  epidemiology*,  etiology
Venezuela / epidemiology

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