Document Detail

Gestational sac volume in missed abortion and anembryonic pregnancy compared to normal pregnancy.
MedLine Citation:
PMID:  20533447     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To compare gestational sac (GS) volume (GSV) between normal pregnancies and missed abortions and anembryonic pregnancies and to determine at what gestational age differences in GS volume become evident. METHODS.: GSV in missed abortion and anembryonic pregnancy were measured using three-dimensional ultrasound and the results were compared with GSV in normal pregnancies. Pregnancies between 6 and 12(+6) gestational weeks of age according to last menstrual period were included in normal pregnancies, missed abortions, and anembryonic pregnancies.
RESULTS: There were 141 normal pregnancies and 82 missed or anembryonic abortions. GSV was significantly larger in normal pregnancies than in missed or anembryonic abortion: 27.51 + or - 25.25 cm(3) and 8.04 + or - 10.54 cm(3), respectively (p < 0.001). When stratified by weeks, statistically significant differences were found beginning at 7 weeks, while GSV measurements were not significantly different between the normal and abnormal pregnancies from 6 to 6(+6) weeks.
CONCLUSION: GSV in missed abortion and anembryonic pregnancies is significantly smaller than in normal pregnancies, starting at 7 weeks of gestational age. This finding may be helpful in the diagnosis of missed abortion or anembryonic pregnancies in selected cases.
Marwan Odeh; Rene Tendler; Mohamad Kais; Vitali Grinin; Ella Ophir; Jacob Bornstein
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of clinical ultrasound : JCU     Volume:  38     ISSN:  1097-0096     ISO Abbreviation:  J Clin Ultrasound     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-12     Completed Date:  2010-11-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401663     Medline TA:  J Clin Ultrasound     Country:  United States    
Other Details:
Languages:  eng     Pagination:  367-71     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Western Galilee Hospital, Nahariya, Israel.
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MeSH Terms
Abortion, Missed / ultrasonography*
Gestational Sac / ultrasonography*
Imaging, Three-Dimensional / methods
Pregnancy Complications / ultrasonography
Pregnancy Trimester, First
Ultrasonography, Prenatal / methods*

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