Document Detail

Gestational sac fluid volume measurements in virtual reality.
MedLine Citation:
PMID:  21520478     Owner:  NLM     Status:  Publisher    
OBJECTIVE: The aim of this prospective cohort study is to evaluate a virtual reality (VR) application for gestational sac fluid volume (GSFV) measurements in first trimester pregnancies and to study the correlation between different embryonic growth parameters. METHODS: We analyzed 180 3D ultrasound scans of 42 healthy women, performed between 5(+5) and 12(+6) weeks gestational age (GA). The 3D datasets were transferred to the I-Space immersive VR system. The V-Scope application is used to create a 'hologram' of the ultrasound image allowing depth perception and interaction with the rendered objects. Volumes can be measured semi-automatically by using a segmentation algorithm. In addition to the GSFV, the total gestational sac volume (GSV) and its diameter (GSD) were measured. The GSV was also calculated using the ellipsoid formula. Previously performed embryonic volume and CRL measurements were included in the study. The outcomes were analyzed using repeated measurement analysis of variance. RESULTS: The GSFV was measured in 78 scans, varying from 434 mm(3) to 81491 mm(3) . The comparison of the GSD formula constructed in our study with a commonly clinically used formula showed an increasing difference with increasing GA. The GSFV/embryonic volume ratio showed a decrease over GA. The GSV calculated by the ellipsoid formula was on average 19.8% greater compared to the GSV measured in VR. CONCLUSIONS: New charts for first trimester GSFV were constructed using VR. A positive correlation between GSFV and GA, CRL and the GSD was found. These growth charts could be promising tools for studying normal and abnormal embryonic development. Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd.
M Rousian; A H J Koning; W C Hop; P J van der Spek; N Exalto; E A P Steegers
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-26
Journal Detail:
Title:  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology     Volume:  -     ISSN:  1469-0705     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9108340     Medline TA:  Ultrasound Obstet Gynecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd.
Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, Erasmus MC, Rotterdam.
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