| Gestational sac aspiration: a novel alternative to dilation and evacuation for management of early pregnancy failure. | |
| | |
MedLine Citation:
|
PMID: 16825069 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
STUDY OBJECTIVE: To explore the effectiveness (success, safety, and complications) of a novel technique of gestational sac aspiration in the management of early pregnancy failure as an alternative to dilation and evacuation (D&E) and conservative management. DESIGN: Prospective historical cohort study comparing effectiveness of gestational sac aspiration (study group) to conservative management (control group) with follow-up until negative quantitative beta human chorionic gonadotropin testing is achieved (Canadian Task Force classification II-1). SETTING: An infertility treatment center. PATIENTS: Among 60 women with failed early pregnancies that were achieved by in vitro fertilization or intrauterine insemination, 20 underwent gestational sac aspiration, whereas 40 chose conservative management. INTERVENTIONS: Gestational sac aspiration was done by transvaginal ultrasound-guided needle aspiration under conscious sedation. Aspirated tissue was sent for karyotyping. Both study and control (conservative management) groups received close follow-up with ultrasound and serial beta human chorionic gonadotropin measurements. MEASUREMENTS AND MAIN RESULTS: There was no significant difference in age, infertility factor, or treatment between study and control groups. Mean gestational age was 8 versus 6 weeks in study and control groups, respectively (p < .05). One and 11 patients required D&E in the study and control groups, respectively (p < .05). Karyotyping was successful in all except one patient in the study group. Chromosomal abnormalities were found in 36% of products of conception. No significant complications occurred CONCLUSION: Gestational sac aspiration is a simple and safe outpatient technique that is more effective than conservative management of early pregnancy failure and less invasive than D&E. Moreover, the technique provides a high probability of obtaining a noncontaminated adequate gestation tissue sample for chromosomal study. |
| | |
Authors:
|
Mohamed F Mitwally; Hafsa Albuarki; Michael P Diamond; Mostafa Abuzeid; Michael M Fakih |
Related Documents
:
|
3919349 - Management of landry-guillain-barré syndrome in pregnancy. 19672089 - Pregnancy and delivery in patients with portal vein cavernoma. 19960049 - Clinical commentary: obstetric and respiratory management of pregnancy with severe spin... 19454019 - Management of appendiceal pseudomyxoma peritonei diagnosed during pregnancy. 9448609 - Management of gallstones in pregnancy. 6623779 - Spontaneous intrapartum rupture of renal hamartoma. 17468429 - Effects of winter stocker growth rate and finishing system on: i. animal performance an... 8079399 - Foetal heart rate in early pregnancy by detection of optimally estimated displacements ... 9481519 - Losses due to porcine reproductive and respiratory syndrome in a large swine farm. |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Journal of minimally invasive gynecology Volume: 13 ISSN: 1553-4650 ISO Abbreviation: - Publication Date: 2006 Jul-Aug |
Date Detail:
|
Created Date: 2006-07-07 Completed Date: 2006-08-31 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 101235322 Medline TA: J Minim Invasive Gynecol Country: United States |
Other Details:
|
Languages: eng Pagination: 296-301 Citation Subset: IM |
Affiliation:
|
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Wayne State University, Detroit, USA. mmitwally@yahoo.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Abortion, Incomplete
/
surgery*,
ultrasonography Adult Chorionic Gonadotropin, beta Subunit, Human / blood Conscious Sedation Female Fertilization in Vitro Gestational Age Humans Insemination, Artificial Middle Aged Pregnancy Pregnancy Trimester, First Prospective Studies Ultrasonography, Prenatal Vacuum Curettage / methods* Vagina / ultrasonography |
| Chemical | |
Reg. No./Substance:
|
0/Chorionic Gonadotropin, beta Subunit, Human |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A surgical technique to adjust bladder neck suspension in laparoscopic Burch colposuspension.
Next Document: Laparoscopic ureteroneocystostomy with psoas hitch.