Document Detail


Gestational effects on placental and serum androgen, progesterone and prolactin-like activity in the mouse.
MedLine Citation:
PMID:  7130889     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The concentrations of androgen, progesterone and prolactin-like activity in serum, placentae and media from placental incubations during the second half of pregnancy in the C3H mouse were evaluated. Serum concentrations, placental content and in-vitro placental release of androgen were raised on day 10 of pregnancy. Serum progesterone levels showed minor fluctuations during the second half of gestation, whereas placenta content and in-vitro release of progesterone were increased on day 10 of gestation. The serum profile of prolactin-like activity showed a significant mid-pregnancy increase on day 10 which did not correlate with placental content or in-vitro placental release of prolactin-like activity. The placental content and in-vitro release of prolactin-like activity were low during mid-pregnancy and increased during the latter days of gestation when serum prolactin-like activity was reduced.
Authors:
M J Soares; F Talamantes
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of endocrinology     Volume:  95     ISSN:  0022-0795     ISO Abbreviation:  J. Endocrinol.     Publication Date:  1982 Oct 
Date Detail:
Created Date:  1982-12-18     Completed Date:  1982-12-18     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0375363     Medline TA:  J Endocrinol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  29-36     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Androgens / metabolism
Animals
Female
Gonadal Steroid Hormones / metabolism*
Hysterectomy
Mice
Mice, Inbred C3H
Organ Culture Techniques
Ovary / metabolism
Placenta / metabolism*
Pregnancy
Pregnancy, Animal*
Progesterone / metabolism
Prolactin / metabolism*
Grant Support
ID/Acronym/Agency:
HD14966/HD/NICHD NIH HHS; RR08132/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Androgens; 0/Gonadal Steroid Hormones; 57-83-0/Progesterone; 9002-62-4/Prolactin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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