| Gestational diabetes mellitus--implications of different treatment protocols. | |
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MedLine Citation:
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PMID: 15270402 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To assess the impact of different management approaches to gestational diabetes mellitus (GDM) on perinatal outcome. PATIENTS AND METHODS: The study group consisted of 2,060 patients with GDM treated in our center from January 1980 through December 1999. Four time periods were defined on the basis of changes in treatment protocols. Perinatal complications were compared between the periods and with normal pregnancy controls. RESULTS: The last two periods (1993-1999) were characterized by lower mean glucose level, lower mean gestational age at delivery, and a decline in macrosomia, shoulder dystocia and perinatal mortality rates, but also by high rates of labor induction and Cesarean delivery. A significant difference was found between the GDM and normal control groups in rates of labor induction (38.6% vs 10.8%, p < 0.001) and Cesarean delivery (34% vs 20%, p < 0.001) for the last period. CONCLUSIONS: Perinatal complications are preventable with good glycemic control and early induction of labor, but at a cost of a higher Cesarean section rate. |
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Authors:
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Yoav Peled; Tamar Perri; Rony Chen; Joseph Pardo; Jacob Bar; Moshe Hod |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of pediatric endocrinology & metabolism : JPEM Volume: 17 ISSN: 0334-018X ISO Abbreviation: J. Pediatr. Endocrinol. Metab. Publication Date: 2004 Jun |
Date Detail:
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Created Date: 2004-07-23 Completed Date: 2004-12-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9508900 Medline TA: J Pediatr Endocrinol Metab Country: England |
Other Details:
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Languages: eng Pagination: 847-52 Citation Subset: IM |
Affiliation:
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Perinatal Division and WHO Collaborating Center for Perinatal Care, Department of Obstetrics & Gynecology, Rabin Medical Center, Petah Tiqva, Israel. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Glucose
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metabolism Cesarean Section / statistics & numerical data Delivery, Obstetric Diabetes, Gestational / drug therapy* Dose-Response Relationship, Drug Drug Administration Schedule Dystocia / epidemiology Female Fetal Macrosomia / epidemiology Gestational Age Humans Hypoglycemic Agents / administration & dosage*, therapeutic use Incidence Infant Mortality Infant, Newborn Insulin / administration & dosage*, therapeutic use Labor Presentation Labor, Induced / statistics & numerical data Pregnancy Retrospective Studies Shoulder Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Hypoglycemic Agents; 11061-68-0/Insulin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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