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Gestational diabetes: evolving diagnostic criteria.
MedLine Citation:
PMID:  21178773     Owner:  NLM     Status:  Publisher    
PURPOSE OF REVIEW: Gestational diabetes mellitus (GDM) is a common complication of pregnancy. There has been controversy and debate about how to optimally diagnose GDM and whether treatment modifies outcomes. We review the current controversies in both the screening and diagnosis of GDM and the benefits of treating GDM. RECENT FINDINGS: Three major studies have been published in the past 2 years that have evaluated these issues. The goal of the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study was to determine the level of maternal glycemia at which adverse fetal/neonatal or maternal outcomes are impacted. Rather than a definitive cut-off, the study found that there was a continuous relationship between maternal glycemia and pregnancy outcomes. Two studies evaluated the effect of treating mild GDM on both maternal and neonatal outcomes. Each found a significant benefit with diagnosis and treatment. SUMMARY: Ideally, the results of the HAPO study will bring order to the current international confusion surrounding the diagnosis of GDM. Recently, the International Association of Diabetes and Pregnancy Study Groups recommended new screening criteria for GDM based on the HAPO study. Professional organizations around the world are currently considering these recommendations.
Michael J Paglia; Donald R Coustan
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-12-20
Journal Detail:
Title:  Current opinion in obstetrics & gynecology     Volume:  -     ISSN:  1473-656X     ISO Abbreviation:  -     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9007264     Medline TA:  Curr Opin Obstet Gynecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
aDivision of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Warren Alpert Medical School of Brown University and Women & Infants Hospital of Rhode Island, Providence, Rhode Island bDivision of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Geisinger Medical Center, Danville, Pennsylvania, USA.
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