| Gestational age at intrauterine myelomeningocele repair does not influence the risk of prematurity. | |
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MedLine Citation:
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PMID: 11844907 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the effect of gestational age at the time of intrauterine myelomeningocele repair on the duration of pregnancy and the gestational age at the time of delivery. METHODS: This study is a retrospective chart review of the maternal and neonatal medical records of all infants undergoing intrauterine myelomeningocele repair at Vanderbilt University Medical Center. Birth weight, gestational age at the time of surgery and gestational age at the time of delivery were recorded. Infants were divided into 2 groups depending on gestational age at the time of surgery, either > or = 25 weeks' gestation (group 1) or < 25 weeks (group 2). Results were expressed as medians and interquartile ranges. Statistical analysis was done using the unpaired (2-sample) t test; p values < or = 0.05 were considered significant. RESULTS: Ninety-five infants were studied. Fifty-one infants were repaired after 25 weeks' gestation (group 1) at a median gestational age of 26.3 weeks (range 25.6-27.6). Their median gestational age at delivery was 34.4 weeks (range 32.6-35.3). Forty-four infants were repaired before 25 weeks' gestation (group 2). Surgery was done at a median gestational age of 23.6 weeks (range 22.4-24.5). The median gestational age at delivery was 34 weeks (range 31.6-35.3; p = 0.88). CONCLUSION: Early intrauterine myelomeningocele repair before 25 week's gestation does not decrease the gestational age at delivery when compared with repair after 25 weeks. |
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Authors:
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A H Hamdan; W Walsh; A Heddings; J P Bruner; N Tulipan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Fetal diagnosis and therapy Volume: 17 ISSN: 1015-3837 ISO Abbreviation: Fetal. Diagn. Ther. Publication Date: 2002 Mar-Apr |
Date Detail:
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Created Date: 2002-03-07 Completed Date: 2002-04-29 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9107463 Medline TA: Fetal Diagn Ther Country: Switzerland |
Other Details:
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Languages: eng Pagination: 66-8 Citation Subset: IM |
Copyright Information:
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Copyright 2002 S. Karger AG, Basel |
Affiliation:
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Division of Neonatology, Vanderbilt University Medical Center, Nashville, TN 37232-2370, USA. ashraf.hamdan@mcmail.vanderbilt.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Fetal Diseases / surgery* Gestational Age* Humans Meningomyelocele / surgery* Obstetric Labor, Premature / epidemiology* Pregnancy Retrospective Studies Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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