| Gestational weight gain and birth outcome in relation to prepregnancy body mass index and ethnicity. | |
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MedLine Citation:
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PMID: 20702110 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The obesity epidemic raises concerns about the impact of excessive and insufficient weight gain during pregnancy. METHODS: We examined the association between gestational weight gain (GWG) and preterm birth, term small- and large-for-gestational-age (SGA and LGA), term birthweight, and term primary Cesarean delivery, considering prepregnancy body mass index (BMI) and ethnicity in a cohort of 33,872 New York City residents who gave birth between 1995 and 2003 and delivered in hospitals elsewhere in New York State. RESULTS: Preterm birth (<37 weeks' gestation) showed a modest U-shaped relationship, with projected GWG of <10 kg and 20+ kg associated with odds ratios of 1.4 and 1.3, respectively, relative to 10 to 14 kg. The pattern was stronger for preterm birth <32 weeks' and for underweight women with low GWG and overweight/obese women with high GWG. Term SGA decreased and term LGA and birthweight increased monotonically with increasing GWG. Primary Cesarean delivery followed the same pattern as LGA, but less strongly. CONCLUSIONS: Although the study is limited by potential selection bias and measurement error, our findings support the contention that GWG may be a modifiable predictor of pregnancy outcome that warrants further investigation, particularly randomized trials, to assess whether the relation is causal. |
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Authors:
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David A Savitz; Cheryl R Stein; Anna Maria Siega-Riz; Amy H Herring |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2010-08-11 |
Journal Detail:
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Title: Annals of epidemiology Volume: 21 ISSN: 1873-2585 ISO Abbreviation: Ann Epidemiol Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2010-12-27 Completed Date: 2011-03-28 Revised Date: 2011-08-01 |
Medline Journal Info:
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Nlm Unique ID: 9100013 Medline TA: Ann Epidemiol Country: United States |
Other Details:
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Languages: eng Pagination: 78-85 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Disease Prevention and Public Health Institute, Mount Sinai School of Medicine, New York, NY 10029, USA. david.savitz@mssm.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Body Mass Index Cesarean Section Cohort Studies Female Humans Infant, Newborn Infant, Small for Gestational Age New York / epidemiology New York City / epidemiology Obesity Overweight Pregnancy / ethnology*, physiology Pregnancy Complications / epidemiology Premature Birth / epidemiology Weight Gain / ethnology* |
| Grant Support | |
ID/Acronym/Agency:
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R21 HD050739/HD/NICHD NIH HHS; R24 HD050924-06/HD/NICHD NIH HHS; R24 HD050924-07/HD/NICHD NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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