Document Detail

Gestational Lyme borreliosis. Implications for the fetus.
MedLine Citation:
PMID:  2685924     Owner:  NLM     Status:  MEDLINE    
Great diversity of clinical expression of signs and symptoms of gestational Lyme borreliosis parallels the diversity of prenatal syphilis. It is documented that transplacental transmission of the spirochete from mother to fetus is possible. Further research is necessary to investigate possible teratogenic effects that might occur if the spirochete reaches the fetus during the period of organogenesis. Autopsy and clinical studies have associated gestational Lyme borreliosis with various medical problems including fetal death, hydrocephalus, cardiovascular anomalies, neonatal respiratory distress, hyperbilirubinemia, intrauterine growth retardation, cortical blindness, sudden infant death syndrome, and maternal toxemia of pregnancy. Whether any or all of these associations are coincidentally or causally related remains to be clarified by further investigation. It is my expectation that the spectrum of gestational Lyme borreliosis will expand into many of the clinical domains of prenatal syphilis.
A B MacDonald
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Rheumatic diseases clinics of North America     Volume:  15     ISSN:  0889-857X     ISO Abbreviation:  Rheum. Dis. Clin. North Am.     Publication Date:  1989 Nov 
Date Detail:
Created Date:  1990-01-03     Completed Date:  1990-01-03     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8708093     Medline TA:  Rheum Dis Clin North Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  657-77     Citation Subset:  IM    
Southampton Hospital, New York.
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MeSH Terms
Borrelia burgdorferi Group / isolation & purification
Diagnosis, Differential
Fetal Death / microbiology
Fetal Diseases / microbiology*
Fetus / microbiology
Lyme Disease / microbiology*
Placenta Diseases / microbiology
Pregnancy Complications, Infectious / microbiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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