Document Detail


Gestational Diabetes: Maternal Weight Gain in Relation to Fetal Growth, Treatment Modality, BMI and Glycemic Control.
MedLine Citation:
PMID:  22185433     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objectives: We sought to determine the impact of maternal weight gain on fetal growth in gestational diabetes (GDM) in relation to treatment modality, body mass index (BMI) and glycemic control. Study Design: 2454 GDMs were evaluated. Obesity was defined as BMI >29; good glycemic control < 100mg/dl; maternal age < and >30 years; parity ±1; large for gestational age (LGA) >90(th) percentile and small for gestational age (SGA) <10(th) percentile. Results: SGA rates were similar in all groups. Obese/overweight diet-treated in glycemic control showed a 4-fold higher rate of LGA compared to insulin treated women. A 36 lb. weight gain in insulin treated patients had a 6-fold higher risk. In poor glycemic control, LGA rates were higher in all BMI/weight gain categories. Logistic regressions for LGA/SGA revealed that level of glycemia, weight gain, parity, obesity and treatment (for LGA only) were significant. Conclusion: Different thresholds used for different maternal BMI categories in addition to the achievement of glycemic control and pharmacological therapy will enhance pregnancy outcome.
Authors:
Orli Most; Oded Langer
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-20
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Atlantic Maternal Fetal Medicine 95 Madison Avenue Morristown, NJ 07960.
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