| Gestatational trophoblastic disease: multimodality imaging assessment with special emphasis on spectrum of abnormalities and value of imaging in staging and management of disease. | |
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MedLine Citation:
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PMID: 22085657 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Gestational trophoblastic disease is a spectrum of disorders of varying malignant potential arising from trophoblastic cells and encompassing hydatidiform moles and persistent trophoblastic neoplasia. Ultrasound is the initial imaging investigation of choice when gestational trophoblastic disease is suspected. Complete hydatiform mole, the most common form of molar pregnancy, usually has a characteristic "cluster of grapes" appearance, especially on second-trimester ultrasounds. Persistent trophobastic neoplasia usually appears as a focal, hypervascular myometrial mass on pelvic ultrasound. Pelvic magnetic resonance imaging is often used as a problem-solving tool in equivocal or complicated cases of gestational trophoblastic disease to assess the degree of invasion into the myometrium and surrounding tissues. Chest x-ray, brain magnetic resonance imaging, and body computed tomography scans are primarily used for the evaluation of metastatic disease, which usually occurs in the context of choriocarcinomas. Choriocarcinoma metastases are usually hypervascular and have a tendency to bleed, features that are reflected in their imaging appearance. |
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Authors:
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Kimia Khalatbari Kani; Jean H Lee; Manjiri Dighe; Mariam Moshiri; Orpheus Kolokythas; Theodore Dubinsky |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current problems in diagnostic radiology Volume: 41 ISSN: 1535-6302 ISO Abbreviation: Curr Probl Diagn Radiol Publication Date: 2012 Jan-Feb |
Date Detail:
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Created Date: 2011-11-17 Completed Date: 2012-01-19 Revised Date: 2012-03-06 |
Medline Journal Info:
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Nlm Unique ID: 7607123 Medline TA: Curr Probl Diagn Radiol Country: United States |
Other Details:
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Languages: eng Pagination: 1-10 Citation Subset: IM |
Copyright Information:
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Published by Mosby, Inc. |
Affiliation:
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Department of Radiology, University of Washington, Seattle, 98195, USA. khalatk@u.washington.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Choriocarcinoma
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diagnosis Female Gestational Trophoblastic Disease / diagnosis*, pathology, therapy Humans Hydatidiform Mole / diagnosis Immunohistochemistry Magnetic Resonance Imaging Positron-Emission Tomography Pregnancy Tomography, X-Ray Computed Ultrasonography, Prenatal Uterine Neoplasms / diagnosis*, pathology, therapy |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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