Document Detail


Germs gone wild.
MedLine Citation:
PMID:  22561817     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The normally harmless behavior of bacteria in the intestinal tract is maintained by community structure and the integrity of host defenses. When either or both of these are compromised, a few disgruntled outcasts can cause a riot, taking down the whole neighborhood (pages 799-806).
Authors:
Namiko Hoshi; Ruslan Medzhitov
Related Documents :
22684917 - Arsenic trioxide induces human pulmonary fibroblast cell death via increasing ros level...
16849487 - A protein associated with toll-like receptor 4 (prat4a) regulates cell surface expressi...
22279587 - A novel atoh1 "self-terminating" mouse model reveals the necessity of proper atoh1 leve...
9642297 - Cell surface ectodomain cleavage of human amphiregulin precursor is sensitive to a meta...
12503647 - Clinical and macroscopic correlates of minicolumnar pathology in autism.
9283037 - Extractibility of structural carbohydrates and lignin deposition in maturing alfalfa in...
Publication Detail:
Type:  Comment; Journal Article     Date:  2012-05-04
Journal Detail:
Title:  Nature medicine     Volume:  18     ISSN:  1546-170X     ISO Abbreviation:  Nat. Med.     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-05-07     Completed Date:  2012-07-27     Revised Date:  2013-07-12    
Medline Journal Info:
Nlm Unique ID:  9502015     Medline TA:  Nat Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  654-6     Citation Subset:  IM    
Affiliation:
Howard Hughes Medical Institute and Yale University Medical School, New Haven, Connecticut, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Anti-Bacterial Agents / pharmacology*
Apoptosis Regulatory Proteins / physiology*
Calcium-Binding Proteins / physiology*
Escherichia coli / drug effects*
Inflammasomes / physiology*
Intestines / microbiology*
Metagenome / drug effects*
Neuronal Apoptosis-Inhibitory Protein / physiology*
Grant Support
ID/Acronym/Agency:
R01 DK071754/DK/NIDDK NIH HHS
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Apoptosis Regulatory Proteins; 0/Birc1e protein, mouse; 0/Calcium-Binding Proteins; 0/Inflammasomes; 0/Ipaf protein, mouse; 0/Neuronal Apoptosis-Inhibitory Protein
Comments/Corrections
Comment On:
Nat Med. 2012 May;18(5):799-806   [PMID:  22522562 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Straight talk with...Chen Zhu.
Next Document:  Protective inflammasome activation in AMD.