Document Detail

Germinoma causing wallerian degeneration. Case report and review of the literature.
MedLine Citation:
PMID:  9420084     Owner:  NLM     Status:  MEDLINE    
Germinomas occurring in the thalamus and basal ganglia sometimes cause atrophy of the cerebral hemisphere on the affected side. The authors present the case of a 12-year-old girl with a germinoma that developed in the basal frontal lobe and cerebral basal ganglia. Magnetic resonance imaging showed atrophy not only of the cerebrum but also of the brainstem. A T2-weighted image revealed an area of high intensity that proved to be wallerian degeneration extending from the corona radiata and internal capsule to the brainstem. The authors suggest that this pathological change may be involved in the development of the symptoms and hemiatrophy associated with germinomas in this region of the brain.
K Nagata; Y Nikaido; T Yuasa; K Fujimoto; Y J Kim; M Inoue
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neurosurgery     Volume:  88     ISSN:  0022-3085     ISO Abbreviation:  J. Neurosurg.     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-01-15     Completed Date:  1998-01-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0253357     Medline TA:  J Neurosurg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  126-8     Citation Subset:  AIM; IM    
Department of Neurosurgery, Osakaminami National Hospital, Kawachinagano City, Osaka, Japan.
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MeSH Terms
Brain Neoplasms / complications*,  pathology
Germinoma / complications*,  pathology
Magnetic Resonance Imaging
Wallerian Degeneration / etiology*,  pathology

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