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Geriatric assessment and chronic kidney disease in the oldest old: The Octabaix study.
MedLine Citation:
PMID:  22863431     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: The prevalence of chronic kidney disease (CKD) in older people is increasing. We determine the proportion of CKD in a sample of 321, 85-year-old community-dwelling subjects, and assess the association of socio-demographic data, global geriatric assessment data and comorbidity with CKD according to the estimated glomerular filtration rate (eGFR) of subjects.
METHODS: Serum creatinine, eGFR (derived in ml/min/1.73m(2) using the Modification of Diet in Renal Disease formula), socio-demographic variables, the Barthel Index (BI), the Spanish version of the Mini-Mental State Examination (MEC), the Mini Nutritional Assessment (MNA), the Charlson Index, the Gait Rating Scale, social risk, quality of life and prevalent chronic diseases were collected.
RESULTS: CKD prevalence was 56.7% for eGFR<60ml/min/1.73m(2), 19.9% for eGFR<45ml/min/1.73m(2) and 6.6% for GFR<30ml/min/1.73m(2). Multiple logistic regression analysis showed that a prior diagnosis of hypertension was associated with an eGFR<60ml/min/1.73m(2) (p<0.008, OR 2.134, 95% CI 1.216-3.744). A diagnosis of heart failure (p<0.001, OR 3.610, 95% CI 1.677-7.771) and a poor score on the quality of life measure (p<0.008, OR 0.9660, 95% CI 0.966-0.995) were associated with an eGFR<45ml/min/1.73m(2).
CONCLUSIONS: More than half of the oldest old in this study had an eGFR<60ml/min/1.73m(2). A history of hypertension was associated with CKD. The group of patients with an eGFR<45ml/min/1.73m(2) was associated with a diagnosis of heart failure and a worse quality of life.
Francesc Formiga; Assumpta Ferrer; Josep Maria Cruzado; Gloria Padros; Marta Fanlo; Beatriz Roson; Ramón Pujol
Publication Detail:
Type:  Journal Article     Date:  2012-03-28
Journal Detail:
Title:  European journal of internal medicine     Volume:  23     ISSN:  1879-0828     ISO Abbreviation:  Eur. J. Intern. Med.     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9003220     Medline TA:  Eur J Intern Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  534-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain; Laboratori Clínic L'Hospitalet-Cornellà, Barcelona, Spain.
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