Document Detail


Geriatric Nutritional Risk Index Predicts Functional Dependency and Mortality in Patients With Heart Failure With Preserved Ejection Fraction.
MedLine Citation:
PMID:  23182759     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background: The clinical significance of nutritional risk assessment in patients with heart failure with preserved ejection fraction (HFpEF) remains undefined. Geriatric nutritional risk index (GNRI) is a simple nutritional assessment tool for elderly subjects. Its predictive value was evaluated in patients with HFpEF, a common HF phenotype in the elderly population. Methods and Results: The present study enrolled 152 consecutive patients (mean age, 77±11 years; male, 53.9%) who were hospitalized with HFpEF at the authors' institution. GNRI on admission was calculated as follows: 14.89×serum albumin (g/dl)+41.7×body mass index/22. Characteristics and mortality (median follow-up of 2.1 years) were compared between 2 groups: low GNRI (<92) with moderate or severe nutritional risk; and high GNRI (≥92) with no or low nutritional risk. Patients in the low-GNRI group were more often female, and had lower serum hemoglobin and sodium, but higher serum blood urea nitrogen (BUN), C-reactive protein, and B-type natriuretic peptide (BNP) compared to those in the high-GNRI group (P<0.05, respectively). Physical activity at discharge measured by Barthel index was significantly lower in the low-GNRI group than the high-GNRI group (P<0.05). On Cox hazard analysis, lower GNRI predicted increased mortality independent of age, gender, prior HF hospitalization, and higher BUN and BNP (P<0.01). Conclusions: GNRI may be useful for predicting functional dependency and mortality in patients with HFpEF.
Authors:
Yoshiharu Kinugasa; Masahiko Kato; Shinobu Sugihara; Masayuki Hirai; Kensaku Yamada; Kiyotaka Yanagihara; Kazuhiro Yamamoto
Related Documents :
24581949 - Critically ill elderly patients in a developing world-mortality and functional outcome ...
23739929 - Impact of coronary artery bypass grafting in elderly patients.
1386809 - Graft replacement of post-traumatic thoracic aortic aneurysm: results without bypass or...
20488319 - A comparative analysis of the outcomes of aortic cuffs and converters for endovascular ...
25075179 - The benefit of atrial septal defect closure in elderly patients.
20103319 - Utility of remote wireless pressure sensing for endovascular leak detection after endov...
21199119 - Efficacy of different concentrations of sevoflurane administered through a face mask fo...
18262159 - Urinary incontinence after radical vulvectomy treated with macroplastique implantation.
23872799 - Prevention of postoperative osteopenia using iv pamidronate: a pilot study.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-25
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  -     ISSN:  1347-4820     ISO Abbreviation:  Circ. J.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Division of Cardiovascular Medicine, Department of Molecular Medicine and Therapeutics, Faculty of Medicine, Tottori University.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Imaging progression of coronary atherosclerosis.
Next Document:  Pregnancy-Related Acute Myocardial Infarction in Japan.