| Geriatric conditions develop in middle-aged adults with diabetes. | |
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MedLine Citation:
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PMID: 20878496 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Geriatric conditions, collections of symptoms common in older adults and not necessarily associated with a specific disease, increase in prevalence with advancing age. These conditions are important contributors to the complex health status of older adults. Diabetes mellitus is known to co-occur with geriatric conditions in older adults and has been implicated in the pathogenesis of some conditions. OBJECTIVE: To investigate the prevalence and incidence of geriatric conditions in middle-aged and older-aged adults with diabetes. DESIGN: Secondary analysis of nationally-representative, longitudinal health interview survey data (Health and Retirement Study waves 2004 and 2006). PARTICIPANTS: Respondents 51 years and older in 2004 (n=18,908). MAIN MEASURES: Diabetes mellitus. Eight geriatric conditions: cognitive impairment, falls, incontinence, low body mass index, dizziness, vision impairment, hearing impairment, pain. KEY RESULTS: Adults with diabetes, compared to those without, had increased prevalence and increased incidence of geriatric conditions across the age spectrum (p< 0.01 for each age group from 51-54 years old to 75-79 years old). Differences between adults with and without diabetes were most marked in middle-age. Diabetes was associated with the two-year cumulative incidence of acquiring new geriatric conditions (odds ratio, 95% confidence interval: 1.8, 1.6-2.0). A diabetes-age interaction was discovered: as age increased, the association of diabetes with new geriatric conditions decreased. CONCLUSIONS: Middle-aged, as well as older-aged, adults with diabetes are at increased risk for the development of geriatric conditions, which contribute substantially to their morbidity and functional impairment. Our findings suggest that adults with diabetes should be monitored for the development of these conditions beginning at a younger age than previously thought. |
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Authors:
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Christine T Cigolle; Pearl G Lee; Kenneth M Langa; Yuo-Yu Lee; Zhiyi Tian; Caroline S Blaum |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. Date: 2010-09-29 |
Journal Detail:
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Title: Journal of general internal medicine Volume: 26 ISSN: 1525-1497 ISO Abbreviation: J Gen Intern Med Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-02-23 Completed Date: 2011-10-24 Revised Date: 2012-03-01 |
Medline Journal Info:
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Nlm Unique ID: 8605834 Medline TA: J Gen Intern Med Country: United States |
Other Details:
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Languages: eng Pagination: 272-9 Citation Subset: IM |
Affiliation:
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Department of Family Medicine, University of Michigan, 300 N. Ingalls, Ann Arbor, MI 48109-2007, USA. ccigolle@umich.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Accidental Falls
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statistics & numerical data Age Factors Aged Aged, 80 and over Aging / pathology* Diabetes Mellitus / epidemiology*, pathology* Dizziness / complications, epidemiology, pathology Female Geriatric Assessment* / methods Health Status* Health Surveys / methods Humans Longitudinal Studies Male Middle Aged Pain / complications, epidemiology, pathology Urinary Incontinence / complications, epidemiology, pathology |
| Grant Support | |
ID/Acronym/Agency:
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1F32AG027649-01/AG/NIA NIH HHS; K08 AG031837-02/AG/NIA NIH HHS; R01 AG 027010/AG/NIA NIH HHS; R01 AG021493A/AG/NIA NIH HHS; U01 AG09740/AG/NIA NIH HHS |
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