| Geographical distribution and demographic characteristics of gestational trophoblastic disease. | |
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MedLine Citation:
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PMID: 20795343 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To outline the geographical distribution pattern of gestational trophoblastic disease (GTD) in a referral center in Bahia, Brazil, and determine the demographics of the disease. STUDY DESIGN: We conducted a study of data retrieved from medical records of 140 GTD patients referred to our Trophoblastic Diseases Center in 2002-2007, assessing geographical distribution across health care districts, demographics, referral sources, and previous pregnancy status. RESULTS: The most common GTD types were hydatidiform mole (106, 75.7%), invasive mole (32, 22.9%), choriocarcinoma (1, 0.7%), and placental site trophoblastic tumor (1, 0.7%). GTD incidence was 8.5 in 1,000 deliveries. Most patients originated from the coastal region (East district), which includes the state capital (77.9%). The 20-34 age group predominated (65%). Education level (67.9% attended elementary school only) and employment rate (42.9%) were low. Secondary hospitals were the principal source of referral (84.3%), followed by self-referrals (15.7%). Regarding previous pregnancy status, 42.1% (n = 59) had had term pregnancy, 39.3% (n = 55) no pregnancy, 15% (n = 21) miscarriage, and 0.7% (n = 1) ectopic pregnancy; 4 patients (2.9%) had previous hydatidiform mole. CONCLUSION: GTD predominated in the peak fertility age group and among patients of unfavorable sociodemographic status. |
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Authors:
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Patrícia Daniela Paranhos B Soares; Izildinha Maestá; Olívia Lúcia Nunes Costa; Rafael Cortés Charry; Adriano Dias; Marilza Vieira Cunha Rudge |
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3780233 - The intrauterine contraceptive device and hydatidiform mole: a negative association. 11766153 - Gestational trophoblastic disease. 2446803 - Cord serum gamma glutamyltransferase in newborns. |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of reproductive medicine Volume: 55 ISSN: 0024-7758 ISO Abbreviation: J Reprod Med Publication Date: 2010 Jul-Aug |
Date Detail:
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Created Date: 2010-08-27 Completed Date: 2010-09-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0173343 Medline TA: J Reprod Med Country: United States |
Other Details:
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Languages: eng Pagination: 305-10 Citation Subset: IM |
Affiliation:
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Trophoblastic Diseases Center, Department of Gynecology and Obstetrics, Botucatu Medical School, São Paulo State University, Brazil. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Distribution Brazil / epidemiology Child Educational Status Employment / statistics & numerical data Female Gestational Trophoblastic Neoplasms / epidemiology* Humans Incidence Parity Pregnancy Uterine Neoplasms / epidemiology* Young Adult |
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