| Geographical distribution of acute lymphoblastic leukaemia subtypes: second report of the collaborative group study. | |
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MedLine Citation:
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PMID: 8418376 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Childhood acute lymphoblastic leukemia (ALL) T and B precursor subtypes have been identified by standardised immunophenotyping in different geographic and ethnic settings. Comparison of the relative frequencies and estimated incidence rates of the major subtypes indicates very similar values, with the striking exception of black childhood populations in Africa in which there appears to be a significant and selective deficit in the incidence of the common (B-cell precursor) subset of ALL. There is suggestive evidence for a similar bias in ALL subtypes in South Africans of mixed ethnic origin and in Mapuche Indians from Chile. Several interpretations of these data are possible but the one favoured attributes these differences primarily to socio-economic factors and patterns of infection in infancy. |
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Authors:
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M F Greaves; S M Colman; M E Beard; K Bradstock; M E Cabrera; P M Chen; P Jacobs; P R Lam-Po-Tang; L G MacDougall; C K Williams |
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Publication Detail:
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Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K Volume: 7 ISSN: 0887-6924 ISO Abbreviation: Leukemia Publication Date: 1993 Jan |
Date Detail:
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Created Date: 1993-02-02 Completed Date: 1993-02-02 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8704895 Medline TA: Leukemia Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 27-34 Citation Subset: IM |
Affiliation:
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Leukaemia Research Fund Centre, Institute of Cancer Research, London, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Age Factors Antigens, CD / analysis Child Child, Preschool Continental Population Groups Female Humans Immunophenotyping Infant Lymphocyte Subsets Male Precursor Cell Lymphoblastic Leukemia-Lymphoma / epidemiology*, immunology |
| Chemical | |
Reg. No./Substance:
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0/Antigens, CD |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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