Document Detail


Geographic pathology of thyroid diseases.
MedLine Citation:
PMID:  6895108     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The thyroid is one of the organs which demonstrates clearly the influence of extrinsic and especially geographically determined influences in the development of diseases. Endemic goiter and cretinism are the most typical examples. The question as to whether thyroid cancer arises more frequently in goiters that in normal thyroids, cannot be answered definitely as yet. But without doubt, the relative frequency of different types of thyroid neoplasms in goiter areas is not the same as in region without endemic goiter. The most common type of thyroid carcinoma observed in a nonendemic region is papillary carcinoma. Follicular and anaplastic carcinomas, however, are more often associated with goiter. Under the influence of iodine prophylaxis, the relative frequency of the different types of thyroid carcinoma approaches that of these carcinomas in nongoiter regions. The malignant hemangioendothelioma is observed nearly exclusively in some Alpine goiter areas. Since the introduction of preventive measures in Switzerland, its occurrence has diminished progressively. In contrast to endemic goiter, focal thyroiditis and even Hashimoto's disease seem to be on the increase since institution of iodine prophylaxis of endemic goiter. As the development of malignant lymphoma may be related to thyroiditis, a possible increase of such tumors should be considered.
Authors:
C Hedinger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pathology, research and practice     Volume:  171     ISSN:  0344-0338     ISO Abbreviation:  Pathol. Res. Pract.     Publication Date:  1981 May 
Date Detail:
Created Date:  1981-11-22     Completed Date:  1981-11-22     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7806109     Medline TA:  Pathol Res Pract     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  285-92     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Congenital Hypothyroidism / epidemiology
Goiter / complications,  epidemiology,  prevention & control
Hemangioendothelioma / epidemiology
Humans
Iodine / therapeutic use
Lymphoma / epidemiology
Switzerland
Thyroid Diseases / epidemiology*,  pathology
Thyroid Neoplasms / complications,  epidemiology,  prevention & control
Thyroiditis / epidemiology
Thyroiditis, Autoimmune / epidemiology
Chemical
Reg. No./Substance:
7553-56-2/Iodine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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