| Genotype of stearoyl-coA desaturase is associated with fatty acid composition in Japanese Black cattle. | |
| | |
MedLine Citation:
|
PMID: 15058385 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To investigate the genetic factors that affect fatty acid composition of beef, we compared the full-length bovine stearoyl-CoA desaturase (SCD) cDNA from 20 Japanese Black steers. Two types of the SCD gene with single nucleotide polymorphisms (SNPs) were observed in the ORF of SCD cDNA, in which an amino acid replacement from valine (type V) to alanine (type A) was predicted. We developed a method for genotyping these two SCD genes based on PCR-RFLP. We have classified 1003 Japanese Black carcasses into three genotypes, VV, VA, and AA, and compared fatty acid composition among them. The SCD type A gene contributed to higher MUFA percentage and lower melting point in intramuscular fat. The SCD genotype was not the only genetic factor contributing to fatty acid composition of Japanese Black steers, but the SCD genotype was considered one of the causes of genetic variation in fatty acid composition of Japanese Black steers. Transcription factors such as sterol regulatory element binding protein-1c (SREBP-1c) may account for the remaining part of the genetic variation in fatty acid composition. |
| | |
Authors:
|
Masaaki Taniguchi; Takeshi Utsugi; Kenji Oyama; Hideyuki Mannen; Masato Kobayashi; Yoshihiro Tanabe; Atsushi Ogino; Soichi Tsuji |
Related Documents
:
|
22505005 - Synthesis of a 3-deoxy-d-manno-octulosonic acid (kdo) building block from d-glucose via... 1458845 - A comparative study on ceramide composition of cetacean brain gangliosides. 18968725 - Design of a composite amperometric enzyme electrode for the control of the benzoic acid... 17253715 - Chemical characterization of lignin and lipophilic fractions from leaf fibers of curaua... 23045145 - Measurement of soluble epoxide hydrolase (seh) activity. 11959025 - Occurrence and tissue distribution of c-series gangliosides in the common squid todarod... |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Mammalian genome : official journal of the International Mammalian Genome Society Volume: 15 ISSN: 0938-8990 ISO Abbreviation: Mamm. Genome Publication Date: 2004 Feb |
Date Detail:
|
Created Date: 2004-04-02 Completed Date: 2004-05-17 Revised Date: 2009-11-19 |
Medline Journal Info:
|
Nlm Unique ID: 9100916 Medline TA: Mamm Genome Country: United States |
Other Details:
|
Languages: eng Pagination: 142-8 Citation Subset: IM |
Affiliation:
|
Laboratory of Animal Breeding & Genetics, Graduate School of Science and Technology, Kobe University, Nada-ku, Kobe 657-8501, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Amino Acid Sequence Analysis of Variance Animals Base Sequence Body Composition* Cattle / genetics* DNA Primers DNA, Complementary / genetics Fatty Acids / analysis, genetics* Japan Molecular Sequence Data Polymorphism, Restriction Fragment Length Sequence Analysis, DNA Stearoyl-CoA Desaturase / genetics* |
| Chemical | |
Reg. No./Substance:
|
0/DNA Primers; 0/DNA, Complementary; 0/Fatty Acids; EC 1.14.19.1/Stearoyl-CoA Desaturase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Mapping of a novel MEN-like syndrome locus to rat chromosome 4.
Next Document: An ecological perspective on bacterial biodiversity.