Document Detail

Genomics and biology of Rudiviruses, a model for the study of virus-host interactions in Archaea.
MedLine Citation:
PMID:  23356326     Owner:  NLM     Status:  In-Data-Review    
Archaeal viruses, especially viruses that infect hyperthermophilic archaea of the phylum Crenarchaeota, constitute one of the least understood parts of the virosphere. However, owing to recent substantial research efforts by several groups, archaeal viruses are starting to gradually reveal their secrets. In the present review, we summarize the current knowledge on one of the emerging model systems for studies on crenarchaeal viruses, the Rudiviridae. We discuss the recent advances towards understanding the function and structure of the proteins encoded by the rudivirus genomes, their role in the virus life cycle, and outline the directions for further research on this model system. In addition, a revised genome annotation of SIRV2 (Sulfolobus islandicus rod-shaped virus 2) is presented. Future studies on archaeal viruses, combined with the knowledge on viruses of bacteria and eukaryotes, should lead to a better global understanding of the diversity and evolution of virus-host interactions in the viral world.
David Prangishvili; Eugene V Koonin; Mart Krupovic
Related Documents :
23269606 - An optimized antiviral modification strategy for prevention of hepatitis b reactivation...
24497986 - Multiple antibody targets on herpes b glycoproteins b and d identified by screening ser...
24464776 - Degradation mechanisms of the tomato yellow leaf curl virus coat protein following inoc...
23080506 - Surveillance of 16 respiratory viruses in patients with influenza-like illness in nanji...
16453696 - The nucleotide sequence of an infectious clone of the geminivirus beet curly top virus.
214226 - Augmented immunogenicity of tumor cell membranes produced by infection with influenza v...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biochemical Society transactions     Volume:  41     ISSN:  1470-8752     ISO Abbreviation:  Biochem. Soc. Trans.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7506897     Medline TA:  Biochem Soc Trans     Country:  England    
Other Details:
Languages:  eng     Pagination:  443-50     Citation Subset:  IM    
*Institut Pasteur, Department of Microbiology, 25 rue du Dr. Roux, Paris 75015, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Membrane vesicles, nanopods and/or nanotubes produced by hyperthermophilic archaea of the genus Ther...
Next Document:  From archaeon to eukaryote: the evolutionary dark ages of the eukaryotic cell.