| Genomic view on the peopling of India. | |
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MedLine Citation:
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PMID: 23020857 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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India is known for its vast human diversity, consisting of more than four and a half thousand anthropologically well-defined populations. Each population differs in terms of language, culture, physical features and, most importantly, genetic architecture. The size of populations varies from a few hundred to millions. Based on the social structure, Indians are classified into various caste, tribe and religious groups. These social classifications are very rigid and have remained undisturbed by emerging urbanisation and cultural changes. The variable social customs, strict endogamy marriage practices, long-term isolation and evolutionary forces have added immensely to the diversification of the Indian populations. These factors have also led to these populations acquiring a set of Indian-specific genetic variations responsible for various diseases in India. Interestingly, most of these variations are absent outside the Indian subcontinent. Thus, this review is focused on the peopling of India, the caste system, marriage practice and the resulting health and forensic implications. |
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Authors:
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Rakesh Tamang; Kumarasamy Thangaraj |
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Publication Detail:
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Type: Journal Article Date: 2012-10-01 |
Journal Detail:
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Title: Investigative genetics Volume: 3 ISSN: 2041-2223 ISO Abbreviation: Investig Genet Publication Date: 2012 |
Date Detail:
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Created Date: 2012-12-05 Completed Date: 2012-12-06 Revised Date: 2013-02-15 |
Medline Journal Info:
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Nlm Unique ID: 101546908 Medline TA: Investig Genet Country: England |
Other Details:
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Languages: eng Pagination: 20 Citation Subset: - |
Affiliation:
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CSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, 500 007, India. thangs@ccmb.res.in. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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